B-(2,3,5,6-Tetrafluoro-4-Methoxyphenyl)boronic Acid

B-(2,3,5,6-Tetrafluoro-4-Methoxyphenyl)boronic Acid - Names and Identifiers

Name	(2,3,5,6-tetrafluoro-4-methoxyphenyl)boronic acid
Synonyms	(2,3,5,6-Tetrafluoro-4-Methoxyphenyl)boronic Acid (2,3,5,6-tetrafluoro-4-methoxyphenyl)boronic acid B-(2,3,5,6-Tetrafluoro-4-Methoxyphenyl)boronic Acid
CAS	871126-20-4
InChI	InChI=1/C7H5BF4O3/c1-15-7-5(11)3(9)2(8(13)14)4(10)6(7)12/h13-14H,1H3

B-(2,3,5,6-Tetrafluoro-4-Methoxyphenyl)boronic Acid - Physico-chemical Properties

Molecular Formula	C7H5BF4O3
Molar Mass	223.92
Density	1.5g/cm³
Melting Point	144-149°C
Boling Point	285.6°C at 760 mmHg
Flash Point	126.5°C
Vapor Presure	0.0013mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.452

B-(2,3,5,6-Tetrafluoro-4-Methoxyphenyl)boronic Acid - Risk and Safety

WGK Germany

B-(2,3,5,6-Tetrafluoro-4-Methoxyphenyl)boronic Acid - Introduction

(2,3,5, boronic acid) is an organic compound with the chemical formula C6H6BF4O2.

Nature:
(2,3,5,) boronic acid is a solid substance with a white to light yellow crystalline appearance. It is soluble in organic solvents (such as chloroform, dimethyl amide and dichloromethane), and also has some solubility in water.

Use:
(2,3,5,) boronic acid is an important reagent in organic synthesis and is commonly used in coordination chemistry and cross-coupling reactions. It can participate as a ligand in metal-catalyzed reactions, for example in Suzuki-Miyaura reactions, to build carbon-carbon bonds. In addition, it can also be used as a starting material or intermediate in the field of pharmaceutical synthesis and material science.

Preparation Method:
(2,3,5) boronic acid can be prepared by generating borate from the acidic site of phenylboronic acid, and then carrying out Suzuki-Miyaura cross-coupling reaction with the corresponding bromine substituent. The specific preparation method can refer to the organic synthesis literature.

Safety Information:
(2,3,5, 2) boronic acid is less toxic to the human body, it still needs to be operated in accordance with conventional laboratory processing methods. Care should be taken to avoid inhalation, swallowing or contact with skin and eyes during use. During operation, it is recommended to wear suitable personal protective equipment, such as laboratory gloves, glasses and laboratory coats. For accidental contact or ingestion, seek medical attention promptly.

Last Update：2024-04-09 19:05:52